Tom Sawyer is a young boy growing up along the Mississippi River in the mid 1800s. Along with his best friend Huckleberry Finn, he spends his days ditching school, fishing, climbing trees and having adventures.

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A little bit in the future, the government has established a brand new organization with the purpose of rescuing lives to respond to the increasingly complicated and varied types of disasters, accidents and crimes that go beyond human comprehension. It is called the "Mobile Emergency Police DRIVE HEAD" force combining specialized police, firefighting and rescue skills. "DRIVE HEAD" is an advanced mobile device that transforms in form factor from car to humanoid walker vehicle. The drivers are high-aptitude, grade school students such as Go Kurumada who collaborate with mobile emergency police adults and rush to crisis situations to secure public safety and preserve the peace for all!

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The anime centers on the battles between the mysterious alien enemy Dark Spinner and the secret defense unit Earth Granner over Earth Energy, the energy generated from the Earth's rotation.

The anime centers on the battles between the mysterious alien enemy Dark Spinner and the secret defense unit Earth Granner over Earth Energy, the energy generated from the Earth's rotation.

Tomie Kawakami is a femme fatale with long black hair and a beauty mark just under her left eye. She can seduce nearly any man, and drive them to murder as well, even though the victim is often Tomie herself. While one lover seeks to keep her for himself, another grows terrified of the immortal succubus. But soon they realize no matter how many times they kill her, the world will never be free of Tomie.

Memories, both good and bad, suffuse the high school experience. Whether it's hanging out with friends or cramming for tests, everyone has something they will remember from that time in their lives. At a certain high school, one class is faced with an event that can cause people to look back on their high school days in sadness: the death of a student. The deceased is not just any student—she's Tomie Kawakami, a popular girl with an almost otherworldly beauty. Her death was particularly gruesome: her body was dismembered and the pieces scattered. As the class tries to make sense of the situation, they are shocked when a familiar voice calls out to them from the doorway, apologizing for being late. With raven hair and a beauty mark under her left eye, this girl is the spitting image of their murdered classmate. But she can't actually be Tomie, right?

Tomo Aizawa and Junichirou "Jun" Kubota are the tightest bros you'd ever see. They roughhouse and spar, but through thick and thin, they've got each other's back. Yet, there's just one small problem: Tomo is in love with Jun! Since she was young, tomboyish Tomo has been just another one of the guys; due to his extreme muscle-brained nature, Jun doesn't notice any of her advances—not even when she explicitly confesses. To add insult to injury, for the longest time, he didn't even realize that she was a girl. Tomo-chan wa Onnanoko! follows the comedic hijinks of Tomo and her friends as she tries to catch Jun's eye and escape the infamous brozone.

Tomo Aizawa and Junichirou "Jun" Kubota are the tightest bros you would ever see. They roughhouse and spar, but through thick and thin, they've got each other's back. Yet, there's just one small problem: Tomo is in love with Jun! Since she was young, tomboyish Tomo has been just another one of the guys; due to his extreme muscle-brained nature, Jun doesn't notice any of her advances—not even when she explicitly confesses. To add insult to injury, for the longest time, he didn't even realize that she was a girl. Tomo-chan wa Onnanoko! follows the comedic hijinks of Tomo and her friends as she tries to catch Jun's eye and escape the infamous brozone.

Yuuichi Katagiri has battled financial hardships his whole life but has learned to stay content and positive thanks to his close circle of friends. To keep a promise he made to them, Yuuichi saves up enough money to join them on the school trip. But when the gathered money mysteriously goes missing, suspicion falls on two of Yuuichi's friends: Shiho Sawaragi and Makoto Shibe, who were in charge of collecting the payments. Although innocent, Shiho and Makoto take responsibility for the failure to protect the money when no one else comes forward. A few days later, Yuuichi and his friends receive mysterious letters which trick each of them into meeting up. Upon arrival, they are ambushed and knocked unconscious. They wake up in a mysterious room in the presence of "Manabu-kun," a character from a controversial children's show that stopped airing due to its malicious content. He informs the group that one of them indirectly gathered them together in order to settle a large debt. They are to play a "friendship game": a series of games that will test the strength of their bond and trust in each other. As the group's faith wavers due to the growing number of secrets and betrayals, Yuuichi must figure out who of his "friends" he can actually trust and ultimately discover the identity of the traitor.